Patient Education


Generic name




Mechanism of action

This carbonic anhydrase inhibitor reduces the aqueous humor production, thus lowering the pressure in the eye.


Treatment of open angle glaucoma or ocular hypertension


Instill 1 drop of brinzolamide ophthalmic solution into the affected eye(s) three times daily, 8 hours apart.

Use with caution in patients with/during
  1. Renal impairment or severe renal disease (with a creatinine clearance less than 30 milliliters per minute)
  2. Hepatic disease
  3. Sulfonamide hypersensitivity
  4. Acute closed angle glaucoma
  5. Pregnancy, breastfeeding, or in children
Common Side Effects
  • Blurred vision
  • Bitter, sour, or unusual taste
Life-Threatening Symptoms
  • Chest pain
  • Jaundice (yellowing of skin or eyes)
Less Common to Rare Side Effects
  • Dermatitis
  • Chest pain
  • Conjunctivitis (inflammation of the conjunctiva)
  • Diarrhea
  • Double vision
  • Dry eye
  • Dry mouth
  • Keratoconjunctivitis
  • Dyspepsia (upset stomach)
  • Eye discomfort or pain
  • Blepharitis (inflammation of the eyelids)
  • Keratitis (corneal inflammation)
  • Tearing
  • Hyperemia (increased amount of blood in eye)
  • Headache
  • Foreign body sensation in eye
  • Dyspnea (shortness of breath)
  • Rhinitis
  • Keratopathy
  • Ocular itching
  • Ocular discharge
  • Nausea
  • Alopecia (hair loss)