Patient Education

Medications

Azopt®
Generic name

Brinzolamide

Concentration

1%

Mechanism of action

This carbonic anhydrase inhibitor reduces the aqueous humor production, thus lowering the pressure in the eye.

Indications

Treatment of open angle glaucoma or ocular hypertension

Dosage

Instill 1 drop of brinzolamide ophthalmic solution into the affected eye(s) three times daily, 8 hours apart.

Use with caution in patients with/during
  1. Renal impairment or severe renal disease (with a creatinine clearance less than 30 milliliters per minute)
  2. Hepatic disease
  3. Sulfonamide hypersensitivity
  4. Acute closed angle glaucoma
  5. Pregnancy, breastfeeding, or in children
Common Side Effects
  • Blurred vision
  • Bitter, sour, or unusual taste
Life-Threatening Symptoms
  • Chest pain
  • Jaundice (yellowing of skin or eyes)
Less Common to Rare Side Effects
  • Dermatitis
  • Chest pain
  • Conjunctivitis (inflammation of the conjunctiva)
  • Diarrhea
  • Double vision
  • Dry eye
  • Dry mouth
  • Keratoconjunctivitis
  • Dyspepsia (upset stomach)
  • Eye discomfort or pain
  • Blepharitis (inflammation of the eyelids)
  • Keratitis (corneal inflammation)
  • Tearing
  • Hyperemia (increased amount of blood in eye)
  • Headache
  • Foreign body sensation in eye
  • Dyspnea (shortness of breath)
  • Rhinitis
  • Keratopathy
  • Ocular itching
  • Ocular discharge
  • Nausea
  • Alopecia (hair loss)