Patient Education


Eye Drops
Generic name

Apraclonidine hydrochloride


0.5%, 1.0%

Mechanism of action

This selective alpha-2 adrenergic agonist reduces the aqueous humor production and thus decreases intraocular pressures.


Treatment of open angle glaucoma or ocular hypertension.


Instill 1 to 2 drops of apraclonidine ophthalmic solution into the affected eye(s) three times daily, 8 hours apart. Consult your doctor for dosing.

Use with caution in patients with/during:
  1. Severe cardiac disease, cerebrovascular disease, or coronary artery disease
  2. Renal impairment or damage or hepatic disease
  3. Pregnancy, breast feeding or in children
Common Side Effects
  • Tearing
  • Eye discomfort
  • Red eyes
  • Foreign body sensation in eye
  • Eyelid swelling
  • Dry mouth
  • Burning and itching eyes
  • Blurred vision
Less Common to Rare Side Effects
  • Allergic reaction
  • Mydriasis (dilated pupils)