Patient Education


Timoptic® & Timoptic-XE®
Generic name

Timolol maleate


0.25%, 0.5%

Mechanism of action

This beta blocker reduces the aqueous humor production and and increasing drainage, thus lowering the pressure.


Treatment of open angle glaucoma, ocular hypertension, aphakic glaucoma, and other various secondary glaucomas.


Instill 1 drop of the 0.25% solution into eye every 12 hours twice every day. Increase to 0.5% solution if needed. Decrease to 1 drop every day if condition is controlled. Consult your doctor for the correct dosage.

Use with caution in patients with/during:
  1. Timolol should NOT be used in patients with preexisting cardiac disease, such as severe bradycardia, advanced AV block, cardiogenic shock, coronary artery disease, vasospastic angina, or congestive heart failure, particularly those with severe left ventricular dysfunction.
  2. Asthma or pulmonary disease (COPD, emphysema, bronchitis)
  3. Diabetes mellitis because it can mask symptoms of hypoglycemia
  4. Hyperthyroidism because it may mask tachycardia
  5. Using an oral beta blocker
  6. Kidney or liver impairments
  7. Raynaud's disease or peripheral vascular disease
  8. Myasthenia gravis
  9. Psoriasis
  10. Pregnancy, breastfeeding, or in children.
Common Side Effects
  • Temporary burning or stinging of eyes
Less Common to Rare SIDE EFFECTS
  • Blepharitis (inflammation of the eyelids)
  • Conjunctivitis (inflammation of the conjunctiva)
  • Keratitis (inflammation of the cornea of the eye)
  • Droopy upper eyelid
  • Double vision
  • Blurred vision
  • Skin rash or itching