Mechanism of action
This beta blocker reduces the aqueous humor production, increases drainage, and alters the blood flow of the eye—thus lowering the pressure.
Treatment of open angle glaucoma and ocular hypertension.
Instill 1 drop of the solution into eye every 12 hours or twice a day.
Use with caution in patients with/during:
- Metipranolol should NOT be used in patients with preexisting cardiac disease, such as severe bradycardia, advanced AV block, cardiogenic shock, coronary artery disease, vasospastic angina, or congestive heart failure, particularly those with severe left ventricular dysfunction.
- Asthma or pulmonary disease (COPD, emphysema, bronchitis)
- Diabetes mellitis because it can mask symptoms of hypoglycemia
- Hyperthyroidism because it may mask tachycardia
- Using an oral beta blocker
- Kidney or liver impairments
- Raynaud's disease or peripheral vascular disease
- Myasthenia gravis
- Pregnancy, breastfeeding, or in children
Common Side Effects
- Stinging or irritation of eye when medicine applied
- Redness of eye or inside of eyelid
- Decreased night vision
- Blurred vision
Less Common to Rare Side Effects
- Crusty eyelids
- Changes in vision