Patient Education


Generic name

Dorzolamide hydrochloride



Mechanism of action

Treatment of open angle glaucoma or ocular hypertension


This carbonic anhydrase inhibitor reduces the aqueous humor production, thus lowering the pressure in the eye.


Instill 1 drop of dorzolamide ophthalmic solution into the affected eye(s) three times daily, 8 hours apart.

Use with caution in patients with/during:
  1. Renal impairment or severe renal disease (with a creatinine clearance less than 30 milliliters per minute)
  2. Hepatic disease
  3. Sulfonamide hypersensitivity
  4. Acute closed angle glaucoma
  5. Pregnancy, breastfeeding, or in children
Common Side Effects
  • Allergic eye reaction (eye itchiness redness or swelling)
  • Bitter taste
  • Stinging or burning on application
  • Sensation of something in the eye
  • Light sensitivity
Life-Threatening Symptoms
  • Allergic reactions in patients who are also allergic to sulfonamides
Less Common to Rare Side Effects
  • Unusual fatigue
  • Blurred vision
  • Dry eyes
  • Tearing
  • Nausea
  • Skin rash